"No one would ever have crossed the ocean if he could have gotten off the ship in a storm."
Not only do I think some would but am certain many have, although far from a majority or even a large number.
The truth is most will avoid difficult challenges, particularly when the odds are against them, the consequences of negative outcome severe.
Whether it be a start-up or a new venture within an established entity, what is your appetite for risk?
Making it more personal, will you tell your boss you think she's wrong?